Peptides are short polymers of amino acid monomers linked by peptide bonds. They are distinguished from proteins on the basis of size, typically containing less than 50 monomer units. A peptide is formed by joining two or more amino acids. When the number of amino acids is less than about 50 these molecules are named peptides while larger sequences are referred to as proteins. The amino acids are coupled by a peptide bond, a special linkage in which the nitrogen atom of one amino acid binds to the carboxyl carbon atom of another.
Peptides are present in every living cell and possess a variety of biochemical activities. They appear as enzymes, hormones, antibiotics, receptors, etc. peptide synthesis is done by coupling the carboxyl group or C-terminus of one amino acid to the amino group or N-terminus of another.
Peptides play a crucial role in fundamental physiological and biochemical functions of life. For decades now, peptide research has been growing as a field in science. They have recently received prominence in molecular biology for several reasons. The first is that they allow the creation of antibodies in animals without the need to purify the protein of interest. This involves synthesizing antigenic peptides of sections of the protein of interest; these are then used to make antibodies in a rabbit or mouse against the protein. Another reasons interest in peptides has grown recently is that they have become instrumental in mass spectrometry, allowing the identification of proteins of interest based on peptide masses and sequence; in this case they are most often generated by in-gel digestion after electrophoretic separation of the proteins.
Peptides have recently been used in the study of protein structure and function. For example, synthetic peptides can be used as probes to see where protein-peptide interactions occur. Inhibitory are also used in clinical research to examine the effects of they on the inhibition of cancer proteins and other diseases.
As interest in peptides has grown, so have techniques for manufacturing it and studying new applications for it. For example, the library is a newly developed technique for protein related study. A library contains a great number of they that have a systematic combination of amino acids; it provides a powerful tool for drug design, protein-protein interactions, and other biochemical as well as pharmaceutical applications.
The interest in peptides is likely to continue into the future. The number of peptides entering clinical trials will likely grow, and the use of peptides conjugated to carbohydrates, antibodies and other proteins is likely to become more frequent. Peptides will not only be used as the active ingredient of new drugs, but as “addictions” to other pharmaceutical agents. Additionally, the range of medical indications that peptides address will grow. Peptide-based substances will continue to find commercial use. Almost certainly peptides will find increased usage to treat obesity, metabolic syndromes and Type 2 diabetes. Peptides will also be used to address currently symptoms and ailments that cannot be treated with drugs.
Another exciting advancement in age management medicine! This peptide is now approved for general use as a substitute for Human Growth Hormone (HGH). HGH is known as the most effective medication to slow the aging process, but has had legal issues in the United States because of abuse. The strict limitations for using HGH are now avoided by using this new peptide (GHRP-6). HGH is a 191-amino acid peptide produced by the pituitary gland and regulated by two chemicals – Growth Hormone Releasing Hormone (GHRH) and Somatostatin (SST). Nutrition and exercise also influences its release. Once HGH is released, it carries out numerous functions in the human body. Under the influence of HGH, cells increase in both size and number, stimulating growth in the body’s cells. It also has the ability to enhance the movement of amino acids through cellular membranes and increases the rate at which these cells convert amino acids into useful proteins. Muscle building and repair, as well as growing new neurons (brain and nerve cells), depend on the presence of adequate HGH. Cognitive decline with aging is due to the absence of adequate HGH. Fat loss with an increase in lean muscle mass has been found to occur even with small doses of HGH.
When does the body actually secrete HGH? The largest quantities are secreted at night while asleep. This is another important reason to get adequate sleep. GHRH (Growth Hormone Releasing Hormone) is responsible for the release of growth hormone while you sleep.
A most interesting part of all is that HGH has the ability to re-grow cartilage! Its use for degenerative joint disease has been mostly ignored and underutilized until now. Rehabilitating old injuries and fractures could be vastly improved with the use of HGH.
In our later years, the body produces less HGH, and its effects are profound. HGH is a great compound for muscle gains and fat-loss with its loss causing the weight gain and loss of muscle mass about which we all complain.
One word of caution: Do not buy HGH online from just any website and attempt to self medicate! The compounds sold on this website are only for research purposes. Only buy from reputed sources.
If you are looking to buy HGH or peptides for therapy, keep in mind that the hormones sold online on various websites could easily be contaminated, toxic or worse and very dangerous to your health. And, using HGH lowers the thyroid output so it requires careful replacement with Thyroxine (T4), not T3. This is yet another reason to make sure you are in a program managed by a qualified practitioner.
Here’s the BIG news! An improvement in HGH increase and regulation is now available. GHRP-6, a 28-amino-acid peptide that signals the human body to begin secreting HGH is now available for use in our age management programs. Use of GHRP-6 to release HGH has many very attractive health benefits such as:
o Decrease body fat
o Promotes collagen growth
o Stimulates growth of new bone
o Reduces excess weight gain
o Reduces Insulin resistance
o Reduces risk of Obesity (Adiposity)
o Stimulates the Immune system, particularly in older patients
Many bodybuilders and athletes have recently started using GHRP-6 in an effort to build more muscle and burn more fat. It is a critical part of the cycling they routinely do, particularly when preparing for a show or competition. GHRP-6 should be part of your age-management protocol, and prescribed by someone very familiar with all its properties and benefits.